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15 Sep 2026 for 2 years

01 Sep 2026

yes

Analytical Chemistry, Physical Chemistry, Inorganic Chemistry, Chemistry, Biochemistry

The Department of Microsystems Engineering (IMTEK) is one of the world's largest and leading academic research centers in the field of microsystems technology. The Laboratory for MEMS Applications (Prof. Dr.-Ing. Zengerle) develops tools for diagnostics, microfluidics and life-science research. For a research project in collaboration with academic and industrial partners, we are looking for a

PhD Student (m/f/d) 80 % 
Optimization of Carbon Electrode Interfaces for Reagent-Free Electrochemical Detection at the Point of Need

In the Electrochemical Biosensors Group 

We are seeking a highly motivated PhD student to contribute to the development of robust carbon electrode interfaces for electrochemical multi-analyte detection in human body fluids. The project combines fundamental surface engineering with translational biosensor development in a highly interdisciplinary research environment.

You will work on the optimization and scalable implementation of biofunctionalization strategies to enhance the robustness, and analytical performance of electrochemical biosensors. A key focus will be the reduction of biofouling and the improvement of signal quality in complex biological matrices, with the aim of enabling reliable sample-to-answer solutions for future diagnostic applications.

Your tasks

• Develop advanced electrode functionalization strategies, including tailored anti-biofouling surface modifications.
• Establish scalable DNA-based biofunctionalization of electrodes.
• Investigate multiplexing strategies for molecular isothermal and aptamer-based detection.
• Integrate molecular assays into sample-to-answer cartridges.
• Analyze and process data to reduce interference from complex biological matrices.

Your profile

• Degree in chemistry, biochemistry, biophysics or related discipline.
• Knowledge of electrochemical methods such as cyclic voltammetry and SWV is an advantage.
• Experience with surface chemistry on gold or carbon, and simple organic syntheses, is an asset.
• Structured, independent, and meticulous working style with strong planning and documentation skills.
• Curiosity to learn new methods and contribute to a multidisciplinary team.
• Entrepreneurial mindset and interest in spin-off formation are an asset.

We offer

• An attractive position in a modern, well-equipped, and industry-oriented research institute, offering exciting insights into medical device research and development.
• Close scientific supervision and comprehensive onboarding into the research topic.
• A fixed-term position for 2 years, with the possibility of extension.

If you are interested, please contact us for further information or submit a comprehensive application including your CV, cover letter, publications, and reference letters:

Dr. Andreas Schreiber                                                            Dr. Nadine Borst

Professur für Anwendungsentwicklung                          Professur für Anwendungsentwicklung

Telefon: +49 761 203-73283                                                   Telefon: +49 761 203 73208

E-Mail: andreas.schreiber at imtek.uni-freiburg.de E-Mail: nadine.borst at imtek.uni-freiburg.de